Whether you're off for a walk in the woods or popping into town, the best baby travel system makes getting around with your little one easy-peasy 🙂
What to look for in the best travel system
It's important to keep in mind that different travel systems are compatible with different car seats, although there is some crossover. The most important thing about buying the best travel system is to make sure it will fit in your car.A big basket is essential! It should be large enough to hold everything you need when you're out with your baby, including the rain cover and your
The car seat will either clip on top of the pushchair's seat component or attach directly to the chassis with the seat component removed. Adapters are sometimes required to fix the car seat onto the pushchair or chassis. Check if these are included. If they aren't, find out what the additional cost will be.A travel system often has a seat component that enables it to be used as a 'normal' pushchair.
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Prediabetes, intervening diabetes and subsequent risk of dementia: the Atherosclerosis Risk in Communities (ARIC) study - DiabetologiaAims/hypothesis The aim of this work was to evaluate whether the association of prediabetes with dementia is explained by the intervening onset of diabetes. Methods Among participants of the Atherosclerosis Risk in Communities (ARIC) study we defined baseline prediabetes as HbA1c 39–46 mmol/mol (5.7–6.4%) and subsequent incident diabetes as a self-reported physician diagnosis or use of diabetes medication. Incident dementia was ascertained via active surveillance and adjudicated. We quantified the association of prediabetes with dementia risk before and after accounting for the subsequent development of diabetes among ARIC participants without diabetes at baseline (1990–1992; participants aged 46–70 years). We also evaluated whether age at diabetes diagnosis modified the risk of dementia. Results Among 11,656 participants without diabetes at baseline, 2330 (20.0%) had prediabetes. Before accounting for incident diabetes, prediabetes was significantly associated with the risk of dementia (HR 1.12 [95% CI 1.01, 1.24]). After accounting for incident diabetes, the association was attenuated and non-significant (HR 1.05 [95% CI 0.94, 1.16]). Earlier age of onset of diabetes had the strongest association with dementia: HR 2.92 (95% CI 2.06, 4.14) for onset before 60 years; HR 1.73 (95% CI 1.47, 2.04) for onset at 60–69 years; and HR 1.23 (95% CI 1.08, 1.40) for onset at 70–79 years. Conclusions/interpretation Prediabetes is associated with dementia risk but this risk is explained by the subsequent development of diabetes. Earlier age of onset of diabetes substantially increases dementia risk. Preventing or delaying progression of prediabetes to diabetes will reduce dementia burden. Graphical Abstract
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