50 years ago, genes eluded electron microscopes

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50 years ago, genes eluded electron microscopes
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Electron m­icroscopes have become much more powerful over the last 50 years.

Molecular biologists can now visualize the larger structures of the cell, such as the nucleus and chromosomes, under the powerful electron microscope. But they have not been able to obtain images of genes on the chromosomes. Nor have they been able to see RNA … or the intricate details of cell membranes, enzymes and viruses.Electron m­icroscopes have become much more powerful over the last 50 years.

, which scientists use to visualize proteins, viruses and bacteria at the molecular level . Capturing detailed images of genes remains elusive, but scientists are inching closer. In 2021, researchers reported using an electron microscope and the molecular scissors CRISPR/Cas9 to visualize proteins

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