A six-month investigation by Science magazine uncovered evidence that images in the much-cited study, published 16 years ago in the journal Nature, may have been doctored.
said Thursday that it uncovered evidence that images in the much-cited study, published 16 years ago in the journal Nature, may have been doctored.
Karl Herrup, a professor of neurobiology at the University of Pittsburgh Brain Institute who wasn’t involved in the investigation, said the findings are"really bad for science." The paper caused"a big splash at the time," said Donna Wilcock, the assistant dean of biomedicine at the University of Kentucky.
"In my own work, [Aβ*56] was not a species ... that we had ever observed," said Dr. Thomas Wisniewski, a professor of neurology at the New York University Alzheimer’s Disease Center. Dr. Karen Ashe, a neuroscientist and professor at the University of Minnesota who co-authored the 2006 paper, said her wish is to retract the study in its entirety, citing that confidence in it has been undermined — but she also maintained that a retraction"does not call the amyloid-beta hypothesis into question."
"The University will follow its processes to review the questions any claims have raised," she said Monday in a statement provided to NBC News.July 14 saying that it was investigating the concerns about the 2006 paper and that"a further editorial response will follow as soon as possible."
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