Alzheimer's drug aducanumab not approved for use in EU

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Alzheimer's drug aducanumab not approved for use in EU
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Charities are disappointed but regulators say there is still little evidence of the drug's benefit.

The European Medicines Agency has said no to approving a new drug for Alzheimer's disease in the EU.

Alzheimer's charities say they are disappointed by the decision because thousands of people are left with no treatment options.At the time, many scientists said there was little evidence from trials of it being of benefit despite it targeting amyloid - a protein that forms abnormal clumps in the brains of people with Alzheimer's.

It's not known whether the company will submit a separate application for approval to the UK regulator, the MHRA.The European Medicines Agency based its decision on two main studies of more than 3,000 patients with early-stage Alzheimer's disease which compared the effects of a low dose and high dose of the drug with a dummy pill.

"Results from the main studies were conflicting and did not show overall that aducanumab was effective at treating adults with early-stage Alzheimer's disease," the EMA said.

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