Bilingual, digital health tool helps reduce alcoholuse, study finds jamanetworkopen
reported similar findings in an RCT conducted among individuals with hazardous and harmful drinking. Given a power of 80%, a significance level of 2-sided α = .05, an SD of 5.2 for the number of binge drinking episodes in the past 28 days, and 1:1 intervention allocation, a sample of 327 participants per group was required to detect a 1.14-episode difference between AB-CASI and standard care.
and preferred language. The statistician used a computer algorithm to generate a permuted block randomization sequence. The sequence was concealed in the OnCore system and allocated after enrollment of a participant by a trained bilingual research assistant.Analyses were conducted according to the intention-to-treat principle and performed using SAS software, version 9.4 .
Similar repeated-measures mixed-model analyses were implemented for each secondary outcome. Comparison of all secondary outcomes between groups was evaluated at a significance level of 2-sidedAlong with stratification factors, the heterogeneity of treatment effects on the primary outcome was assessed for subgroups based on prespecified factors assessed at baseline .
; biculturalism, Hispanicism, and Americanism are categories approximating acculturation referring to respective levels of comfort and involvement in activities that are classified as. These exploratory subgroup analyses were conducted within the GLMM framework by including the interactions of treatment, time, and subgroup factors. Differences between AB-CASI and standard care were calculated for each level of the subgroup and were compared using linear contrasts.
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