Bills vs. Patriots predictions: NFL picks, odds and betting offers

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Bills vs. Patriots predictions: NFL picks, odds and betting offers
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Our NFL betting writer brings you his best Bills vs. Patriots predictions and picks for their NFL Week 18 showdown, which is live Sunday on CBS at 1 p.m. ET.

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The Patriots find themselves in a win-or-go-home scenario, as a victory allows them to clinch a playoff berth, while a loss effectively ends their season. Meanwhile, Buffalo can make a giant leap toward clinching the No. 1 seed in the AFC if it can down its division rival for the second time in as many months.Buffalo has won five of the last six meetings with the Patriots , prevailing by at least 12 points in four of those victories.

Highmark Stadium hasn’t been comforting for opponents, either, as the Bills have posted a 6-1 home record with an average margin of victory of 16.3 points. Considering New England has relied on its defense to help generate a hefty portion of its scoring as of late, don’t be surprised if the Patriots’ offense simply can’t keep up with Buffalo’s.

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