A panel of experts that advises the CDC said the Pfizer and Moderna mRNA COVID-19 vaccines should be the preferred shots for adults in the U.S. because the Johnson & Johnson shot carries the risk of a rare but potentially fatal side effect. More:
In an emergency meeting Thursday, the CDC’s Advisory Committee on Immunization Practices, or ACIP, voted unanimously to state a preference for the mRNA vaccines over the Johnson & Johnson. The vote came the panel heard a safety update on cases of thrombosis withsyndrome, or TTS, a condition that causes large clots that deplete the blood of platelets, resulting in uncontrolled bleeding.
The risk of dying from TTS after a Johnson & Johnson shot is extremely rare. There is an estimated 1 death for every 2 million doses of the vaccine given in the general population. That risk is higher for women ages 30 to 49, rising to about 2 deaths for every 1 million doses given in this age group.
In updating the safety information on Johnson & Johnson today, the panel noted that the warning label had not sufficiently lowered the risk of death from TTS. Doctors seem to be aware of the condition because none of patients who had developed TTS had been treated with the blood thinner, which can make the syndrome worse. But patients continued to die even after the label was added, the panel noted, because TTS can progress so quickly that doctors simply don’t have time to treat it.
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