Could HIV Meds Help Slow Advanced Cancers?

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Could HIV Meds Help Slow Advanced Cancers?
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A drug that revolutionized the treatment of HIV may show promise in halting the progression of colon cancer.

For the new study, Ting and his colleagues explored the potential of just one widely used HAART medication:The trial involved 32 patients, all of whom were diagnosed with advanced colon cancer that had spread widely, despite a series of standard but unsuccessful cancer treatments.

Lamivudine was administered without any other form of cancer therapy. The result, Ting noted, was that eight of the patients saw the progression of their cancer come to a halt, while one more achieved a"mixed response." In fact, Greenbaum said, lamivudine's impact on tumor cells is so similar to its impact on HIV that it amounts to a"surprising" form of"viral mimicry."

"We are…trying to better understand which cancers are more dependent on this RT activity, so that we can have more precision in the patients that might benefit from this therapy," he said, stressing that the prospects for this type of cancer intervention"are still in the early days."

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