Gene-therapy test launches pivotal year for precise genome-editing technique known as base editing
Credit: Martin Steinthaler/GettyA clinical trial that recently treated its first participant will test whether base-editing — a genome-editing method related to the CRISPR–Cas9 system — can safely be used to make precise, single-letter changes to a DNA sequence in a cholesterol-regulating gene without breaking both strands of DNA first, as CRISPR–Cas9 would do.
Both tests are expected to report results in 2023, and further base-editing treatments are working their way through the pipeline towards clinical trials. “It’s very exciting that the first clinical trials are starting, with CRISPR–Cas9 and now also with base editing,” says Gerald Schwank, who studies the use of genome editing to treat diseases at the University of Zurich, Switzerland. “We’ve got a lot to learn.
Ireland Latest News, Ireland Headlines
Similar News:You can also read news stories similar to this one that we have collected from other news sources.
Heart gene therapy to remove young sudden death riskExperts hope to permanently correct or silence the inherited genetic material that is involved.
Read more »
Real Pod Wednesdays: Gene Smith Joins the Show from Big Ten Media DaysGene Smith joins the show for a wide-ranging conversation on college sports and Ohio State athletics and we recap Big Ten Media Days on this week’s episode of Real Pod Wednesdays.
Read more »
Former Alabama coach Gene Stallings suffers third strokeFormer Alabama football coach Gene Stallings has 'a little setback.'
Read more »
What Turmeric Does to Your Body: Health BenefitsTurmeric contains curcumin, which has powerful anti-inflammatory and antioxidant properties that have been shown to be effective against heart disease, arthritis, Alzheimer's disease, gastrointestinal disorders and metabolic syndrome.
Read more »
HSMTMTS’ Matt Cornett Guesses Iconic Disney Lyrics From ‘Encanto, ‘Frozen’ & MoreWe put matt_cornett_'s Disney knowledge to the test. 😉 Watch the video now! HighSchoolMusical HSMTMTS disneyplus hsmseries
Read more »
How Much You Need To Walk Every Day To Cut Your Risk Of Heart DiseaseData suggests there's a certain number of minutes you should aim for to improve your cardiovascular health. Here's how you can sneak them in.
Read more »