A Dead Cells animated series is set to arrive next year with ten episodes each around seven minutes long.
animated series arrives in 2024, and Motion Twin says it"blends humor, action, and a dollop of madness." Check out the teaser trailer below..."Made of course by Bobbypills, the French studio behind our animated trailers, the show takes place on a cursed island that has been racked by a strange plague.
The show will have ten episodes, all around seven minutes long, and will be co-produced by Animation Digital Network, a French streaming service. It'll first be available exclusively in France but will then be available worldwide.. What do you make of this announcement? Let us know in the comments!
Ireland Latest News, Ireland Headlines
Similar News:You can also read news stories similar to this one that we have collected from other news sources.
Dead Cells is getting a 10-episode animated series next yearDead Cells - the superb rogue-like action-platformer from Motion Twin and subsidiary Evil Empire - is being turned into…
Read more »
Embryonic vitamin D deficiency programs hematopoietic stem cells to induce type 2 diabetes - Nature CommunicationsEnvironmental conditions during pregnancy contribute to offspring metabolic disease. Here, the authors show that immune cells reprogrammed in utero by maternal vitamin D deficiency increase lifetime diabetes risk in the offspring and are sufficient to transplant diabetes.
Read more »
A ZFYVE21-Rubicon-RNF34 signaling complex promotes endosome-associated inflammasome activity in endothelial cells - Nature CommunicationsNLRP3 inflammasomes trigger release of IL-1 to promote tissue injury. Here, Li et al identify a ZFYVE21-Rubicon-RNF34 (ZRR) signaling complex localizing to endosomes and modulating complement-mediated inflammasome activity in vitro and in vivo.
Read more »
Scientists create synthetic human embryos using stem cells in major breakthroughThe move could provide insight into the causes of miscarriages, but also raises a number of legal and ethical dilemmas.
Read more »
Prominent epigenetic and transcriptomic changes in CD4+ and CD8+ T cells during and after pregnancy in women with multiple sclerosis and controls - Journal of NeuroinflammationBackground Multiple sclerosis (MS) is a neuroinflammatory disease in which pregnancy leads to a temporary amelioration in disease activity as indicated by the profound decrease in relapses rate during the 3rd trimester of pregnancy. CD4+ and CD8+ T cells are implicated in MS pathogenesis as being key regulators of inflammation and brain lesion formation. Although Tcells are prime candidates for the pregnancy-associated improvement of MS, the precise mechanisms are yet unclear, and in particular, a deep characterization of the epigenetic and transcriptomic events that occur in peripheral T cells during pregnancy in MS is lacking. Methods Women with MS and healthy controls were longitudinally sampled before, during (1st, 2nd and 3rd trimesters) and after pregnancy. DNA methylation array and RNA sequencing were performed on paired CD4+ and CD8+ T cells samples. Differential analysis and network-based approaches were used to analyze the global dynamics of epigenetic and transcriptomic changes. Results Both DNA methylation and RNA sequencing revealed a prominent regulation, mostly peaking in the 3rd trimester and reversing post-partum, thus mirroring the clinical course with improvement followed by a worsening in disease activity. This rebound pattern was found to represent a general adaptation of the maternal immune system, with only minor differences between MS and controls. By using a network-based approach, we highlighted several genes at the core of this pregnancy-induced regulation, which were found to be enriched for genes and pathways previously reported to be involved in MS. Moreover, these pathways were enriched for in vitro stimulated genes and pregnancy hormones targets. Conclusion This study represents, to our knowledge, the first in-depth investigation of the methylation and expression changes in peripheral CD4+ and CD8+ T cells during pregnancy in MS. Our findings indicate that pregnancy induces profound changes in peripheral T cells, in both MS and health
Read more »
Understanding the developmental link: vitamin D's role in metabolic disease riskUnderstanding the developmental link: vitamin D's role in metabolic disease risk NatureComms UWMedicine vitamind VD vitaminddeficiency deficiency diabetes type2diabetes T2D metabolicdisease
Read more »