Diabetes Drug Metformin Might Keep Severe COVID Away

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Diabetes Drug Metformin Might Keep Severe COVID Away
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Common diabetes drug effective against COVID-19.

Dr. William Schaffner, medical director of the National Foundation for Infectious Diseases, thinks metformin could be useful in treating COVID-19.

“Metformin clearly has an anti-inflammatory activity. There also are suggestions that it might have a direct antiviral activity, but I think it's more the anti-inflammatory response,” Schaffner said. Since metformin is already FDA-approved, doctors could use it off-label to help high-risk COVID patients — and Bramante thinks they should consider doing so.

women and children, with few medication interactions, she added. Its most common side effect is gastrointestinal disturbances, and those typically go away if the dose is reduced.Schaffner would like to see more evidence, however, before the drug is used to either treat or prevent COVID-19.

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