An expert has shared five signs that suggest you have high blood sugar levels
High blood sugar affects people who have been diagnosed with diabetes and it can often turn serious if left untreated or ignored.
The pancreas overworking could make it less efficient and so could lead to type 2 diabetes. According to charity group the Diabetes and Wellness Foundation, 90 percent of cases in the UK are Type 2. Feeling tired Cassandra said: "Of course, feeling tired can have many causes! But it can be an indication that your body is not efficiently taking glucose into your cells to use for energy, meaning your blood sugar stays high.”
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Intermittent fasting vs. calorie restriction: which diet reduces the risk of type 2 diabetes more?Intermittent fasting vs. calorie restriction: which diet reduces the risk of type 2 diabetes more? NatureMedicine UniofAdelaide intermittentfasting caloriedefecit calorierestriction T2D type2diabetes research diet news
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The roles of dietary lipids and lipidomics in gut-brain axis in type 2 diabetes mellitus - Journal of Translational MedicineType 2 diabetes mellitus (T2DM), one of the main types of Noncommunicable diseases (NCDs), is a systemic inflammatory disease characterized by dysfunctional pancreatic β-cells and/or peripheral insulin resistance, resulting in impaired glucose and lipid metabolism. Genetic, metabolic, multiple lifestyle, and sociodemographic factors are known as related to high T2DM risk. Dietary lipids and lipid metabolism are significant metabolic modulators in T2DM and T2DM-related complications. Besides, accumulated evidence suggests that altered gut microbiota which plays an important role in the metabolic health of the host contributes significantly to T2DM involving impaired or improved glucose and lipid metabolism. At this point, dietary lipids may affect host physiology and health via interaction with the gut microbiota. Besides, increasing evidence in the literature suggests that lipidomics as novel parameters detected with holistic analytical techniques have important roles in the pathogenesis and progression of T2DM, through various mechanisms of action including gut-brain axis modulation. A better understanding of the roles of some nutrients and lipidomics in T2DM through gut microbiota interactions will help develop new strategies for the prevention and treatment of T2DM. However, this issue has not yet been entirely discussed in the literature. The present review provides up-to-date knowledge on the roles of dietary lipids and lipidomics in gut-brain axis in T2DM and some nutritional strategies in T2DM considering lipids- lipidomics and gut microbiota interactions are given.
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Pokémon Scarlet and Violet’s next 7-star Tera Raid features a ghost-type Typhlosion | VGCThe next 7-star Tera Raid in Pokémon Scarlet and Violet will let players catch a Typhlosion with the Ghost Tera type.
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Why we should grow native bluebellsIt’s almost bluebell season, when we walk through woodlands cloaked in carpets of the trademark late spring flowers. But do the bluebell woods we visit harbour English bluebells or Spanish varieties, which it is feared will reduce our native variety?
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Hay fever sufferers given warning as 'alarming' levels of pollen forecastAn expert has warned that one type of pollen could reach its highest level to date
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The effect of surgical weight loss on diabetes complications in individuals with class II/III obesity - DiabetologiaAims/hypothesis The aim of this study was to determine the effect of bariatric surgery on diabetes complications in individuals with class II/III obesity (BMI | 35 kg/m2). Methods We performed a prospective cohort study of participants with obesity who underwent bariatric surgery. At baseline and 2 years following surgery, participants underwent metabolic phenotyping and diabetes complication assessments. The primary outcomes for peripheral neuropathy (PN) were a change in intra-epidermal nerve fibre density (IENFD, units=fibres/mm) at the distal leg and proximal thigh, the primary outcome for cardiovascular autonomic neuropathy (CAN) was a change in the expiration/inspiration (E/I) ratio, and the primary outcome for retinopathy was a change in the mean deviation on frequency doubling technology testing. Results Among 127 baseline participants, 79 completed in-person follow-up (age 46.0 ± 11.3 years [mean ± SD], 73.4% female). Participants lost a mean of 31.0 kg (SD 18.4), and all metabolic risk factors improved except for BP and total cholesterol. Following bariatric surgery, one of the primary PN outcomes improved (IENFD proximal thigh, +3.4 ± 7.8, p|0.01), and CAN (E/I ratio −0.01 ± 0.1, p=0.89) and retinopathy (deviation −0.2 ± 3.0, p=0.52) were stable. Linear regression revealed that a greater reduction in fasting glucose was associated with improvements in retinopathy (mean deviation point estimate −0.7, 95% CI −1.3, −0.1). Conclusions/interpretation Bariatric surgery may be an effective approach to reverse PN in individuals with obesity. The observed stability of CAN and retinopathy may be an improvement compared with the natural progression of these conditions; however, controlled trials are needed. Graphical abstract
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