Study explored the impact of dietary vitamin A on gut microbiota and intestinal transcriptome, revealing its potential in Alzheimer's disease (AD) pathology and cognitive functions in mice.
By Tarun Sai LomteMar 28 2024Reviewed by Susha Cheriyedath, M.Sc. A recent study published in the journal Frontiers in Nutrition evaluated the effects of dietary vitamin A on the gut microbiota and intestinal transcriptome.
Study: Dietary vitamin A modifies the gut microbiota and intestinal tissue transcriptome, impacting intestinal permeability and the release of inflammatory factors, thereby influencing Aβ pathology. Image Credit: Nefedova Tanya / Shutterstock Accordingly, mice were trained for four days, followed by a 60-second search for a hidden platform. A detection test was performed after five days of training, and the time to find the platform was determined. Two trials were administered on the concluding day; one required locating the platform's position in its absence within 60 seconds, and in the other, the time to locate the platform was measured.
Related StoriesThe impact of vitamin A on dietary intake and body weight changes in APP/PS1 mice. The changes in body weight of APP/PS1 mice among different groups. The changes in dietary vitamin A intake among different groups of APP/PS1 mice. *Indicates compared with the VAN group, p < 0.05 indicates statistical significance
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