An electrochemical carbon–carbon bond-forming reaction.
The formation of bonds between carbon atoms is key to the synthesis of molecules used in diverse applications, including pharmaceuticals, agrochemicals and materials. However, it remains challenging to join together carbon atoms that are connected to four other atoms .
The coupling of carbon atoms that are connected to three other atoms is more straightforward and better established. But the coupling of-hybridized carbon atoms produces molecules that have greater three-dimensionality than do molecules produced by the coupling of-hybridized carbons, which are flatter. Having such three-dimensionality improves the success of drug molecules in clinical trials
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