Eliminating gene SRC-3 in immune cells triggers effective long-lasting anti-cancer response BCMHouston PNASNews
. The findings encourage pursuing further investigations to determine the value of this approach to treat the human disease.
Over the years, the O'Malley lab and colleagues have been particularly interested in SRC-3 and its role in cancer. SRC-3 is not only highly expressed in alland plays a role in cancer growth, but it is also strongly expressed in Tregs that regulate the immune response to cancer.
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