Evolutionary history of transformation from chronic lymphocytic leukemia to Richter syndrome - Nature Medicine

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Evolutionary history of transformation from chronic lymphocytic leukemia to Richter syndrome - Nature Medicine
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Integrative genomic and transcriptomic analyses reveal molecular events defining Richter transformation from CLL, and highlight the potential of cell-free DNA for early detection. cfDNA getz_lab lesh_lab RomainGuieze ErinMParry

I.L. serves as a consultant for PACT Pharma, Inc.; has stock in, is on the board of and serves as a consultant for ennov1 LLC.; and is on the board of and holds equity in Nord Bio, Inc. C.J.W., G.G., B.A.K. and Z.L. are inventors on a patent: ‘Compositions, Panels, and Methods for Characterizing Chronic Lymphocytic Leukemia’ . C.J.W., G.G., E.M.P., I.L. and R.G. are named as inventors on U.S. provisional patent application serial number 63/244,625, filed on 15 September 2021, and U.S.

serves as an advisor for Abbvie, AstraZeneca, Beigene, Behring, Cytomx Therapy, Dava Oncology, Janssen, Juno Therapeutics, Oncotracker, Pharmacyclics and Targeted Oncology; receives funding support from Abbvie, Acerta Pharma, Bristol Meyer Squib, Celgene, Genentech, MEI Pharma, Pharmacyclics, Sunesis, TG Therapeutics and Tolero Pharmaceuticals; and participates on the Data Safety Monitoring Committee for Agios Pharm, AstraZeneca, BMS-Celgene, Cytomx Therapeutics, Dren Bio, Janssen, MorphoSys...

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