Exploring viral loads of SARS-CoV-2 Omicron BA.5 and BA.2 sublineages medrxivpreprint SARSCoV2 COVID19 Omicron Sublineage
By Bhavana KunkalikarNov 1 2022Reviewed by Aimee Molineux In a recent study posted to the medRxiv* preprint server, researchers compared the viral loads of severe acute respiratory syndrome coronavirus 2 Omicron BA.5 and BA.2 sublineages.
Polymerase chain reaction testing was used to detect 774 coronavirus disease 2019 patients who visited the Tokyo Medical and Dental University hospital between 1 February 2021 and 31 August 2022. Samples from nasopharyngeal swabs were collected during the patient's initial outpatient visit. In this investigation, the first sample was collected from each patient.
In particular, 215 samples had the mutations 501Y, 484A, 452L, and 371L/373P, referred to as BA.1, whereas 184 samples had the mutations 501Y, 484A, 452L, and 371F/373P, referred to as BA.2. Individuals belonging to the BA.2 cohort, six BA.2.12.1 samples having 501Y, 484A, 452Q, and 371F/373P mutations, as well as ten unidentified BA.2 samples having 501Y, 484A, 452M, and 371F/373P mutations.
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