Extra-Virgin Olive Oil Enhances the Blood–Brain Barrier Function in Mild Cognitive Impairment: A Randomized Controlled Trial

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Extra-Virgin Olive Oil Enhances the Blood–Brain Barrier Function in Mild Cognitive Impairment: A Randomized Controlled Trial
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Researcher finds oliveoil to improve brain health, memory in mildcognitiveimpairment individuals auburnu

]. We identified each participant’s hippocampus and parahippocampal gyrus and estimated BBB permeability across all voxels within these regions. To do this, we used the T1 images obtained before and after injection of the contrast agent in the subtraction pipeline reported by Chassidim et al. [

]. This method provided a numerical value for BBB permeability for each hippocampal/PHG voxel in each subject at both baseline and 6-month scans. These were then subjected to statistical tests to determine whether there is a group × session interaction effect.Venous blood samples were collected from all participants at baseline and end of olive oil consumption. Plasma and serum were separated, aliquoted, and stored at −80 °C within 30 min of collection.

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