World’s first personalised mRNA cancer vaccine for melanoma halves risk of patients dying or the disease returning, according to results
A personalised cancer vaccine for melanoma halves the risk of patients dying or the disease returning, according to trial resultsThe world’s first personalised mRNA cancer vaccine for melanoma halves the risk of patients dying or the disease returning, according to trial results that doctors described as “extremely impressive”.
Known as mRNA-4157 , the jab is custom-built for each patient and tells their body to kill any remaining cancer cells and prevent the disease coming back. MRNA vaccines teach a person’s body how to make a protein that will trigger an immune response, without using a live virus.Health watchdog urges people to draw up health plans for when they lack capacity to make decisionsI Am Not an Alcoholic: ‘I would like a non-alcoholic Guinness,’ says the man.
The 157 patients in the phase 2b trial had high-risk melanomas and either had the jab, developed by Moderna and Merck, alongside the immunotherapy Keytruda or were given only Keytruda. “We are encouraged by the latest results,” said Kyle Holen, Moderna’s head of development, therapeutics and oncology. “These findings reinforce our commitment to advancing this innovative treatment.”
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