Few Transgender Teens Discontinue Hormones in Young Adulthood

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Few Transgender Teens Discontinue Hormones in Young Adulthood
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New research finds most transgender adolescents who took puberty-blocking drugs and then cross-sex hormone treatment continued to do so as they entered adulthood. The study negates past findings that large numbers of youth regret transitioning. MedTwitter

Most adolescents with gender dysphoria who took puberty-blocking drugs for at least 3 months and then progressed to cross-sex hormone treatment were still taking hormones as they entered adulthood, new research of patients at a pioneering Dutch clinic shows.

The cohort included 720 youth: 220 were assigned male at birth and 500 were assigned female at birth . At the start of puberty-blocking treatment with a gonadotrophin-releasing hormone agonist, the median age of patients was 14.1 years for AMAB and 16.0 years for AFAB. About 40% of adolescents assessed by the gender clinic in Amsterdam go on to receive hormonal treatment.

However, he cautioned the study is limited by the fact that the data come from a registry and they only looked at prescriptions issued and not compliance.

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