Researchers discover exploiting microbiome bacteria in patients with lunginfections improves low oxygen levels
DSM 32247. Ormendes SA, Lausanne, Switzerland which gifted the product Sivomixx® is responsible for the standardization of the product in terms of enzymatic content, biochemical and immunological profile. The oral bacteriotherapy involved the use of 2,400 billion bacteria per day. The formulation was administered in three equal doses per day.No sample-size calculations were performed. The categorical variables were compared using the χtest and showed as absolute frequencies and percentage.
Notably, at admittance, a significantly higher proportion of patients with respiratory failure was present in the group treated with oral bacteriotherapy respect to the OB– one . Therefore, all enrolled patients were classifiable in stage III of the syndromic classification proposed by the Italian Society of Anesthesia and Resuscitation .
For what concerns drug therapies, both groups did not differ for number, type, and combinations of administered drugs during the period of hospitalization . The median time from diagnosis to the start of oral bacteriotherapy administration was 1 day and duration of treatment was 14 days for all patients.. Drug therapies administered to the groups of subjects as determined by the administration of bacteriotherapy.
The oral bacterial administration was associated with the disappearance of diarrhea in all the patients within 7 days. Interestingly, a large proportion of OB+ subjects solved diarrhea within 24 h and almost the totality within 3 days (
Ireland Latest News, Ireland Headlines
Similar News:You can also read news stories similar to this one that we have collected from other news sources.
New research on nirmatrelvir resistance in SARS-CoV-2 using powerful replicon cell culture systemsIn a recent study posted to the bioRxiv* preprint server, researchers at Emory University used severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Washington (WA.1) and Omicron (BA.1) strains to test for mutations that could result in resistance to the antiviral drug nirmatrelvir.
Read more »
Physical and technical challenges attracted Kone to EnglandThe physical challenge and the technique required to be successful here is what brought Ismael Kone to play in England with Watford.
Read more »
Efficacy and safety of prone position in COVID-19 patients with respiratory failure: a systematic review and meta-analysis - European Journal of Medical ResearchBackground Prone position has already been demonstrated to improve survival in non-COVID acute respiratory distress syndrome and has been widely performed in COVID-19 patients with respiratory failure, both in non-intubated and intubated patients. However, the beneficial effect of the prone position in COVID-19 pneumonia still remains controversial. Therefore, we aimed to evaluate the effectiveness and safety of the prone position compared with the non-prone in non-intubated and intubated COVID-19 patients, respectively. Methods We searched the MEDLINE, EMBASE, and Cochrane databases, as well as one Korean domestic database, on July 9, 2021, and updated the search 9 times to September 14, 2022. Studies that compared prone and non-prone positions in patients with COVID-19 were eligible for inclusion. The primary outcomes were mortality, need for intubation, and adverse events. Results Of the 1259 records identified, 9 randomized controlled trials (RCTs) and 23 nonrandomized studies (NRSs) were eligible. In the non-intubated patients, the prone position reduced the intubation rate compared with the non-prone position in 6 RCTs (n = 2156, RR 0.81, P = 0.0002) and in 18 NRSs (n = 3374, RR 0.65, P = 0.002). In the subgroup analysis according to the oxygen delivery method, the results were constant only in the HFNC or NIV subgroup. For mortality, RCTs reported no difference between prone and non-prone groups, but in NRSs, the prone position had a significant advantage in mortality [18 NRSs, n = 3361, relative risk (RR) 0.56, P | 0.00001] regardless of the oxygen delivery methods shown in the subgroup analysis. There was no RCT for intubated patients, and mortality did not differ between the prone and non-prone groups in NRSs. Adverse events reported in both the non-intubated and intubated groups were mild and similar between the prone and non-intubated groups. Conclusion For non-intubated patients with COVID-19, prone positioning reduced the risk of intubation, particular
Read more »
Ginger supplement significantly reduced length of hospital stay in individuals with COVID-19 - Nutrition & MetabolismBackground Evidence from previous studies has suggested that ginger extract exhibits the potential as an alternative treatment for Coronavirus disease 2019 (COVID-19). Here, we want to investigate whether ginger supplement improves the clinical manifestation of hospitalized COVID-19 individuals. Methods A total of 227 hospitalized individuals with COVID-19 were randomized to either the control (n = 132) or intervention group (n = 95). The intervention group took ginger supplement orally at the dosage of 1.5 g twice daily, until they were discharged from the hospital. Both groups received the same standard of general medical care during hospitalization, and the length of stay was recorded and compared between groups. Results Among all participants, a significant reduction in hospitalization time (the difference between the treatment and control groups was 2.4 d, 95% CI 1.6–3.2) was detected in response to the ginger supplement. This effect was more pronounced in men, participants aged 60 years or older, and participants with pre-existing medical conditions, relative to their counterparts (P-interactions | 0.05 for all). Conclusion Ginger supplement significantly shortened the length of stay of hospitalized individuals with COVID-19. Trial registration: The trial was registered on the Chinese Clinical Trial Registry (ChiCTR2200059824).
Read more »
Will Lunar New Year travel cause Covid catastrophe in China?It's the first day of China's Lunar new year holiday - traditionally a day when people make up to 2 billion trips across the country to visit their home towns. But this year it's happening in the shadow of soaring Covid cases. fatimamanji reports.
Read more »
Thousands cross Hong Kong-China border as Covid restrictions end\n\t\t\tKeep abreast of significant corporate, financial and political developments around the world.\n\t\t\tStay informed and spot emerging risks and opportunities with independent global reporting, expert\n\t\t\tcommentary and analysis you can trust.\n\t\t
Read more »