Detectives confirm they have shared their concerns with the families of James and Barry Gillespie.
The Daily Record has previously reported they may haveAsked if he thought the brothers might be dead Det Insp Michael Lochrie told BBC Scotland: "It is a possibility and it's something that we can't rule out.
Det Insp Lochrie, of the force's Organised Crime and Counter Terrorism Unit, added: "Despite previous appeals, which have focused on The Netherlands and Brazil, we are still appealing for anyone who has information about the current whereabouts of James and Barry Gillespie to get in touch with Police Scotland.
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