Health Check newsletter: What do leukaemia cure claims really mean?

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Health Check newsletter: What do leukaemia cure claims really mean?
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The success of gene therapy in treating a fatal form of leukaemia is cause for celebration, but we don't yet know how common such results will be

THOMAS COEX/AFP via Getty Images

I can understand his concerns. Journalism on cancer research is notorious for overhyping small studies, generating false hopes in those affected by this disease. Gene therapy, though, has done better. In the approach used in the new study, people have some of their immune cells removed. A gene is added to these, which encodes an artificial receptor that recognises leukaemia cells, and the resulting CAR-T cells are then multiplied and reinfused into the cancer patient.

It would be wonderful if it worked for everyone. But other cancer treatments like chemotherapy and radiotherapy don’t have 100 per cent success rates either, and are still highly valued weapons against these diseases. That is the big question of course – are those who go into remission really cured? Interestingly, the “c-word” wasn’t used in the scientific paper – but during the press conference, the lead researcher mentioned it often.

Many cancer researchers are now trying their hardest on this, coming up with ever-more complicated forms of the artificial receptors and giving the modified immune cells other genes for extra defences.

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