High-dose ivermectin does not reduce COVID-19 symptom duration among mild-to-moderate outpatients DukeMedSchool Ivermectin COVID19 SARSCoV2 SymptomDuration
By Pooja Toshniwal PahariaFeb 27 2023Reviewed by Benedette Cuffari, M.Sc. In a recent study published in JAMA, researchers evaluate the efficacy of ivermectin in a maximum dosage of 600 μg/kg/day over six days in treating early mild-to-moderate coronavirus disease 2019 .
It remains unknown whether a daily dose of ivermectin 600 μg/kg can reduce the duration of symptoms or prevent hospital admissions in individuals with mild-to-moderate SARS-CoV-2 infections in outpatient settings. Individuals were recruited between February 16, 2022, and July 22, 2022, and followed up through November 10, 2022. COVID-19 diagnosis was confirmed by polymerase chain reaction assay or SARS-CoV-2 antigen testing, including at-home tests.
Immunology eBook Compilation of the top interviews, articles, and news in the last year. Download a free copy The other study drug under investigation during the period was fluvoxamine. Proportional hazards regression modelling was performed and the hazard ratios were calculated. Ivermectin was supplied in bottles comprising 7.0 mg tablets to participants’ homes.
Study findings Among the study participants, 59% were female with a median age of 48 years and 84% were fully vaccinated against COVID-19. In both groups, the median duration for sustained recovery from COVID-19 was 11 days.
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