High lipoprotein(a) levels linked to repeated heart disease events in older adults CHDresearch Cardiovascular Health RiskFactors HeartDisease Dubbo Australia CHDPrevention LipidProfile CHD tandfonline
By Dr. Chinta SidharthanJun 18 2023Reviewed by Benedette Cuffari, M.Sc. In a recent study published in the journal Current Medical Research and Opinion, researchers report that high lipoprotein levels were linked to repeated coronary heart disease events in older adults.
Lipoprotein is believed to be a similar risk factor as LDL for cardiovascular disease and mortality. Therefore, by reducing lipoprotein levels, patients may be at a reduced risk for future cardiovascular events. Baseline observations for demographic, cardiovascular, and psychosocial risk assessments were recorded. A range of medical assessments was performed, including blood tests, anthropometry, resting electrocardiogram, and blood pressure. Blood samples were collected after 12 hours of fasting to measure glucose, lipoproteins, and lipids levels.
A modified enzyme-linked immunosorbent assay called sandwich ELISA was used to measure the levels of lipoprotein. LDL cholesterol levels were also determined and corrected for the cholesterol content from lipoprotein. Other significant differences between those with and without recurrent coronary heart disease included older age, male gender, low high-density lipoprotein cholesterol levels, and high triglyceride levels. Additionally, many recurrent coronary heart disease cases used anti-hypertensive therapies, atrial fibrillation, or diabetes. LDL cholesterol levels were not higher in individuals with recurrent coronary heart disease events.
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