The study, published in the New England Journal of Medicine, adds to the growing body of research on the mental health effects of hormone therapy for trans youths.
, published Wednesday in the New England Journal of Medicine, evaluated 315 transgender youths between 12 to 20 years old, with an average age of 16, over the course of two years while they were being treated with gender-affirming hormone therapy.
Researchers found that, on average, participants reported increases in positive emotions, life satisfaction and appearance congruence. Those increases were associated with decreases in depression and anxiety symptoms. “Those who had not gone through substantial gender-incongruent puberty had higher scores for appearance congruence, positive affect, and life satisfaction and lower scores for depression and anxiety at baseline than youth who had undergone substantial endogenous puberty,” meaning the puberty associated with their assigned sex, the researchers wrote.
Second, they wrote that physical changes that result from going through testosterone-driven puberty, such as a deeper voice, might be “more pronounced and observable” than those associated with an estrogen-driven puberty.
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