Genetic engineering deployed to insert gene for human insulin into a bacterium, thus harnessing the substance for widespread use
The story of the discovery of the hormone insulin, the elucidation of its role in controlling blood sugar levels and its development as a successful treatment for diabetes isHormones are chemical messengers that affect/control many bodily processes. Insulin plays a key role in regulating blood sugar levels — a lack of insulin or an inability to react adequately to insulin causesGlucose is the body’s main source of energy, and the brain relies exclusively on it.
In Type 2 diabetes, also known as Resistance Diabetes, body cells are resistant to insulin and less well able to absorb glucose from the blood. Depending on the level of insulin resistance, Type 2 diabetics may also take insulin injections to manage blood glucose levels. Pharmaceutical company Eli Lilly then entered the picture and quickly developed a method for higher purification of insulin from pigs/cows. More than two tonnes of starting material was required to produce 8oz of purified insulin. But by the early 1970s, a problem emerged. Supplies of animal pancreases declined and the prevalence of Type 1 diabetes grew, precipitating fears of insulin shortages.
Diabetes Fda-Food-And-Drug-Administration
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