Increased interleukin-6 is associated with long COVID-19: a systematic review and meta-analysis - Infectious Diseases of Poverty

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Increased interleukin-6 is associated with long COVID-19: a systematic review and meta-analysis - Infectious Diseases of Poverty
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A Scoping Review published in Infectious Diseases of Poverty finds the increased interleukin-6 is associated with long COVID and high levels of this immune mediator could serve as a predictor of long COVID.

Characteristics of the included studies. According to the described search strategy, 469 articles were retrieved . A total of 60 articles were excluded for duplication, while the remaining 409 articles underwent an initial screening. On the basis of the type of article, title, and abstract, 376 articles were excluded, and a total of 33 full-text articles were assessed for eligibility.

Eleven articles that did not relate to long COVID-19 or with an IL-6 value not provided were excluded. Finally, a total of 22 studies were retained for this work, 16 of which were used in the meta-analyses . A total of 21/22 included studies were of high quality , while only one study had a NOS score = 5.

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