Poorsleep linked to years of poor cardiovascularhealth BMCMedicine
]. In brief, more than half a million participants aged 40 to 69 provided informed consent to enrolment and data linkage to electronic health records. The baseline assessment included self-reported questionnaires, a computer-assisted personal interview, physical examinations, and biological sampling. The UK Biobank keeps removing all records of dropping out participants, so retrieving loss of follow-up is inapplicable.
Primary care data on clinical events and prescriptions covered 227,834 participants. Primary care clinical events were coded with Read codes version 2 or Clinical Terms Version 3 , while prescriptions were mainly coded with Read v2, British National Formulary , or Dictionary of Medicines and Devices .
: Method S2 and Fig. S1-2. The primary care was censored to September 2018, with data availability varied between participants and was determined by the registration date with a primary care practice.We identified the incidence of hospital inpatient disease events based on ICD-9 and ICD-10: CVD [
Ireland Latest News, Ireland Headlines
Similar News:You can also read news stories similar to this one that we have collected from other news sources.
"Racing is the best medicine" for NASCAR's Max GutierrezMax Gutierrez returns to NASCAR racing this weekend for the first time since he was injured in a tragic car wreck in January that also claimed the life of his younger brother.
Read more »
Very low-calorie ketogenic diet (VLCKD): an antihypertensive nutritional approach - Journal of Translational MedicineBackground Obesity is accompanied by hormonal, inflammatory and endothelial alterations. These alterations induce a stimulation of several other mechanisms that contribute to the hypertensive state and to increase the cardiovascular morbidity. This pilot, open - label, single- center, prospective clinical trial aimed to evaluate the effect of very low- calorie ketogenic diet (VLCKD) on blood pressure (BP) in women with of obesity and hypertension. Methods A total of 137 women, who met the inclusion criteria and accepted to adhere to VLCKD, were consecutively enrolled. Assessment of anthropometric parameters (weight, height, and waist circumference), body composition (through bioelectrical impedance analysis), systolic (SBP) and diastolic blood pressure (DBP) and blood sample collection were carried out at baseline and after 45 days of the active phase of VLCKD. Results After VLCKD all the women experienced a significant reduction in body weight and an overall improvement of body composition parameters. In addition, high sensitivity C reactive protein (hs- CRP) levels were significantly diminished (p | 0.001), while phase angle (PhA) increased by almost 9% (p | 0.001). Interestingly, both SBP and DBP were significantly improved (-12.89% and − 10.77%, respectively; p | 0.001). At baseline, SBP and DBP showed statistically significant correlations with body mass index (BMI), waist circumference, hs-CRP levels, PhA, total body water (TBW), extracellular water (ECW), Na / K ratio, and fat mass. Even after VLCKD, all correlations among SBP and DBP with the study variables were statistically significant, except for the association between DBP and Na / K ratio. Changes (%) in both SBP and DBP were associated with ∆BMI%, ∆PhA% and ∆hs- CRP levels (p | 0.001). In addition, only ∆SBP% was associated with ∆waist circumference (p = 0.017), ∆TBW (p = 0.017), and ∆fat mass (p | 0.001); while only ∆DBP% was associated with ∆ECW (p = 0.018), and ∆Na / K ratio (p = 0.048). After adju
Read more »
Codon-specific KRAS mutations predict survival benefit of trifluridine/tipiracil in metastatic colorectal cancer - Nature MedicineA combination of real-world evidence and a reanalysis of phase 3 clinical trial data unveils KRAS codon G12 mutations as a biomarker of resistance to trifluridine/tipiracil in metastatic colorectal cancer.
Read more »
Evidence that cross-reactive immunity from common human coronaviruses can influence response to SARS-CoV-2In a recent study published in the journal Vaccines, researchers in Saudi Arabia and the United States examined immune responses and immunoglobulin G (IgG) cross-reactivity in individuals infected with Middle East respiratory syndrome coronavirus (MERS-CoV) and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
Read more »
China's efforts to influence standards fake and floppingBut Carnegie Endowment worries a handful are real, and that the ITU is 'susceptible to manipulation'
Read more »