Latent tuberculosis infection results for the United States from the 2019–2020 National Health and Nutrition Examination Survey EIDjournal CDCgov TB tuberculosis latentTB infection disease
Background The US Centers for Disease Control and Prevention receives the clinical and demographic data for TB cases annually from the District of Columbia and all states. LTBI is the precursor to TB and is not reported across most states. The National Health and Nutrition Examination Survey cycles are the primary national data source of LTBI. NHANES includes cross-sectional surveys examining the health of the non-institutionalized, civilian US population.
The survey examined LTBI among older people aged 60 or above and non-US-born individuals aged > 6. Participants were tested for TB using an interferon-γ release assay. These specific sub-populations were selected due to the potential of TB complications in older subjects, the high risk of LTBI-to-TB progression in non-US-born individuals, and the high test positivity in these individuals in prior studies.
Overall, 1,123 older subjects, including non-US- and US-born individuals, were tested for TB. Of these, 81 individuals were TB-positive, including 35 non-Hispanic black individuals. In the older age group, test-positive individuals were less likely to be non-Hispanic White, have a high-school diploma, and are more likely to be non-US born and live in poverty.
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