Long-term follow-up study of chronic pancreatitis patients highlights need for closer monitoring after surgery amcollsurgeons
at the University of Cincinnati College of Medicine."In this study, we have long-term follow-up examining survival and cause of death in these patients well after that surgical period, and what we see is that survival continues to decline even five years out from surgery."
Researchers evaluated long-term survival rates and outcomes from 493 patients who underwent 555 operations for chronic pancreatitis at the University of Cincinnati Medical Center between 2000 and 2020. They found a high 1-year survival rate among patients but a much lower 10-year survival rate. Pancreatitis caused by alcohol use and/or smoking, along with persistent smoking and opioid use after surgery, was associated with worse outcomes, pointing to a need for closer monitoring after surgery.
Distal pancreatectomy, which involves removal of the body and head of the pancreas and, in some cases, the spleen, in 12.8%. With follow-up ranging from 26 to 118 months , 38.1% were still smoking, 16.4% were abusing alcohol, and 29.6% were using opioids daily as of their last follow-up visit.opioid useOverall, 165 study patients died at a median age of 50.6 years. The most common cause of death was infections , followed by cardiovascular disease , complications of diabetes , substance abuse , and progressive chronic pancreatitis or failure to thrive . Other notable causes of death were cancer and suicide .
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