The Nobel Prize for Medicine or Physiology has been awarded to two scientists, Katalin Karikó and Drew Weissman
the Trinity College Immunologist said he has seen no negative reaction to this prize from other scientists."'Is that deserving, was that discovery big enough?'"Simply because, we all know, what Katalin and Drew achieved was so important scientifically but also important medically."The COVID-19 vaccines, the RNA vaccines, and the AstraZeneca one of course as well and Johnson & Johnson, they've saved millions and millions of lives - that's the bottom line.
"She knew there was a thing called pseudouridine in certain types of RNA, they're called transfer RNA," he said."A thing called TLR3 - toll-like receptor 3 - is the thing that's sensing the RNA and driving the inflammatory process, as if it's a virus. "Karikó's paper in 2005 - which by the way I refereed - was able to modify the RNA, put in pseudouridine and now TLR3 no longer recognises the RNA."It also stabilised it and it made it more protein," he added.Share this article
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