Majority of Adults With EoE Achieve Histologic Response After SFED

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Majority of Adults With EoE Achieve Histologic Response After SFED
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For most patients with eosinophilic esophagitis, symptoms can improve after patients complete the six-food elimination diet GastroTwitter EoE

EoE is an immune-mediated inflammatory condition characterized by pathologic inflammation of eosinophils in the esophagus that leads to esophageal dysfunction. In adults, this inflammation typically leads to difficulty with swallowing and to food impaction.

The researchers classified patients as full responders if eos/hpf levels were <15 after the 6-week food elimination diet. The researchers also recorded food triggers if food reintroduction was pursued after the diet. Altogether, 123 patients achieved eos/hpf of <15 after initial or extended diet elimination. This implies that 31% of patients who don't initially respond may do so on a second attempt, the study authors write.

"Their study suggests that single-food or six-food group elimination is a viable option for adult patients with EoE," he said."Other groups have seen similar results in pediatrics."Gonsalves and colleagues reviewed data from patients who were seen in the clinic during the past 3 years and found that 60% of responders and 35% of nonresponders are maintaining some form of dietary restriction.

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