Moderna has launched early-stage human trials for an mRNA vaccine to treat HIV, the company announced to investors on Thursday.
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The immunogens being tested in the trial were developed by teams at IAVI and Scripps Research. The vaccine uses the same mRNA technology developed by Moderna for its COVID-19 vaccine. Each of the four sites will enroll 56 healthy, HIV-negative adult volunteers. 48 of those will receive one or two doses of the vaccine, with 32 of those volunteers being given the booster shot. An additional eight volunteers will be given the booster by itself. Volunteers will then be monitored for six months after the last dose, with their immune responses being analyzed at the molecular level.
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