NEW: Moderna announces that a booster dose of its bivalent COVID-19 vaccine performs better against two circulating versions of the omicron variant, compared with a booster shot of its original formula.
that were on average 15.1-fold higher, compared with the company's prototype vaccine, when measured in adults approximately nine and a half months after prior vaccination. The safety and tolerability profile of the bivalent booster remains similar to the original vaccine, with adverse events "generally lower than the second dose of the primary series," Moderna said.
Moderna's analysis, as described in the press release, has not been vetted through the normal scientific review process. Once the dominant viral strain, the BA.5 subvariant is now estimated to account for about 30% of all new COVID-19 cases in the United States, according to the CDC. Newer versions of the omicron variant, such as BQ.1 and BQ.1.1, are slowly overtaking as a proportion of estimated cases, at 20% and 24%, respectively. These subvariants are descendants of BA.5.
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