Monkeypox vaccine modeling study provides road map for vaccination

Monkeypox vaccine modeling study provides road map for vaccination CMAJ CMAJ

Model structure. Health states and transitions. Cities, risk groups and contact networks. Note: E=exposed, H=isolating, I=infectious, R=recovered, risk=risk of monkeypox virus infection or transmission, defined by numbers of sexual partners , S=susceptible, V=vaccinated. Arrow opacity is qualitatively related to the chance of sexual contact formation from any group to another . Rate definitions can be found in Appendix 1, Section A .

Researchers modeled two hypothetical cities as interconnected networks with a combined GBMSM community size of 100,000. The team then varied the characteristics of the two cities across a range of plausible settings and simulated roll-out of 5,000 vaccine doses shortly after the first detected case of MPXV.

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