Puzzled scientists are searching for the cause of a strange and alarming outbreak of severe hepatitis in young children across Europe and Alabama.
on 12 April about the U.K. outbreak, noting that vomiting and jaundice–yellowing of the skin and the whites of the eyes—are common symptoms.
“The leading hypotheses center around adenovirus—either a new variant with a distinct clinical syndrome or a routinely circulating variant that is more severely impacting younger children who are immunologically naïve,” the Scottish investigators wrote. Researchers continue to study other possibilities. For example, the immunological effects of a prior episode of COVID-19 might have left children more vulnerable to infection or the illness could be a long-term complication of COVID-19 itself. An unidentified toxin has also not been ruled out.
In the United States, CDC is helping the Alabama Department of Public Health investigate nine cases of hepatitis in children ranging in age from 1 to 6 years old and who also tested positive for adenovirus. The cases have occurred since October 2021, Kristen Nordlund, a CDC spokesperson, said in the statement emailed to“CDC is working with state health departments to see if there are additional U.S. cases, and what may be causing these cases,” she wrote.
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