Naltrexone-Bupropion and Behavior Therapy, Alone and Combined, for Binge-Eating Disorder: Randomized Double-Blind Placebo-Controlled Trial

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Naltrexone-Bupropion and Behavior Therapy, Alone and Combined, for Binge-Eating Disorder: Randomized Double-Blind Placebo-Controlled Trial
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People with binge-eatingdisorder benefit from specific behavioraltherapy and medication yale

shows weight values at the baseline and posttreatment assessments, along with changes. Mixed models of percent weight loss revealed a significant interaction between BWL and time and a significant main effect of time , but no significant interaction between medication and time and no significant three-way interaction . Comparisons between the BWL and no-BWL conditions were significant at the posttreatment assessment and at all monthly time points except month 1.

Mixed models of depression scores revealed a significant interaction between BWL and time and a significant main effect of time . Depression scores decreased significantly more in the BWL conditions than in the no-BWL conditions, with the difference statistically significant at later monthly time points and at the posttreatment assessment .

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