Researchers followed nearly 1,800 patients over the course of 18 months and found the drug 'resulted in moderately less decline on measures of cognition and function,' compared to patients who received a placebo.
A sign at Biogen Inc. headquarters in Cambridge, Mass., June 7, 2021.Promising data shows that an Alzheimer's drug can slow cognitive decline.the New England Journal of Medicine
However, the companies noted that "longer trials are warranted to determine the efficacy and safety of Lecanemab in early Alzheimer's disease."Boston Globe via Getty Images, FILE Over the course of 18 months, patients in the Lecanemab group saw their score go up by 1.21 points in comparison with patients in the placebo group, who saw their score go up by 1.66 points.There were some adverse events in the trial, the companies said, including about 20% of Lecanemab-treated patients who experienced brain swelling or brain bleeding, although side effects were largely asymptomatic.
The Alzheimer's Association said it was "encouraged" by the news and called on the U.S. Food and Drug Administration to give accelerated approval of Lecanemab. The FDA is currently slated to make an approval decision by Jan. 6, 2023. The statement continued, "Treatments that deliver tangible benefits to those living with mild cognitive impairment due to Alzheimer's and early Alzheimer's dementia are as valuable as treatments that extend the lives of those with other terminal diseases."BSIP/Universal Images Group via Getty Images
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