Nirmatrelvir/ritonavir reduces the risk of COVID-19-associated hospitalization CIDJournal niramatrelvir ritonavir covid COVID19 SARSCoV2 hospitalization
By Neha MathurMay 10 2023Reviewed by Lily Ramsey, LLM In a recent study published in the Clinical Infectious Diseases Journal, researchers performed a retrospective cohort study between March 15 and October 15, 2022, among severe acute respiratory syndrome coronavirus 2 -infected high-risk outpatients in Québec, Canada.
All trial participants were unvaccinated and received the drug within five days of symptom onset or COVID-19 diagnosis, which reduced the risk of hospitalization and death by 89%. It was the date of the first prescription of nirmatrelvir/ritonavir for the treatment group and the first COVID-19 positive test for the control group.
The team also recorded 226 health conditions for each study participant using a case-mix classification based on the Population Grouping Methodology . Eventually, 2.1% of drug recipients sought hospital admission, and the hospitalization rate was highest in older outpatients.
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