The 26-year-old was injured playing for club side Millwall at the weekend
The Scots are hoping to do the double on the former world and European champions to book their place at Euro 2024, following a 2-0 win at Hampden in March.
It means he joins fellow Lanarkshire star Kieran Tierney on the sidelines, with the Real Sociedad defender ruled out, possibly until Christmas, with a hamstring issue suffered in a 3-0 over Athletic Bilbao at the start of the month. Two other Lanarkshire stars are fit for the squad with Cambuslang's Kenny McLean of Norwich City called up alongside Bologna's Lewis Ferguson, from Hamilton.
Failing that, if Spain draw or defeat Norway in a qualifier on Sunday, Scotland's spot at the finals would be secured then.
Ireland Latest News, Ireland Headlines
Similar News:You can also read news stories similar to this one that we have collected from other news sources.
Kevin Nisbet in Scotland injury blow as he's ruled out of SpainThe Millwall forward is awaiting the full extent of an injury sustained against Hull City
Read more »
Over 77,000 homes & businesses in Lanarkshire can now access ultrafast broadbandThe new full fibre services are now available to thousands of households and businesses in places across North and South Lanarkshire.
Read more »
Man fled cops at Lanarkshire clinic said 'it was worth a try' after being foundBradley Hannon, 26, attempted to flee from Hairmyres Hospital, East Kilbride. He was eventually captured by officers after having successfully evaded them for over a day.
Read more »
Lanarkshire man admits torching firefighter's cars outside his homeWilliam Lambie admitted causing £33,000 of damage by wilfully setting fire to the Mercedes and Ford Kia.
Read more »
Body found found in search for missing Lanarkshire mumLisa Wotherspoon, 37, disappeared from Vulcan Street, Motherwell, where she was last seen at around 6am on Friday, September 29.
Read more »
South Lanarkshire pupils get copy of new kids book thanks to housebuilder‘Cones and Building Homes’ was commissioned by Persimmon Homes and written by author Chris Madeley. The book is part of a series in which cones discover the world around them.
Read more »