The data are growing that COVID booster jabs enhance protection — but their durability, impact and ability to quash the new variant are unknown
“Our immune response to these vaccines is really robust if you are healthy. Barring any massive surprise variants, I don’t see any reason why we’d need to get a fourth dose,” Ellebedy toldThe new variant could change the immunological picture. Among Omicron’s many mutations, few seem likely to compromise T cells’ ability to recognize the virus and attack infected cells, notes Alessandro Sette, a vaccine biologist at the La Jolla Institute for Immunology in California.
If they don’t, however, vaccine makers have a back-up plan: at least four companies have started developing Omicron-specific booster candidates. It will take months before any of those come to market, so public-health agencies continue to recommend standard boosters for the time being.Will boosters help to curb the pandemic?
“We are not yet seeing any reduction in the effectiveness of the boosters,” says Dvir Aran, a biomedical data scientist at the Technion — Israel Institute of Technology in Haifa.
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