A protein that builds up in the brains of Alzheimer’s patients could be causing skin cancer cells to spread easier once they reach the brain - via healthing_ca healthing
Chris Arnold,Alzheimer’s disease, is believed to be the result of the accumulation of certain proteins in the brain that leads to the slow death of neurons. GETTY
A protein that builds up in the brains of Alzheimer’s patients could be causing skin cancer cells to spread easier once they reach the brain.Cancer DiscoveryResearchers chose to focus on melanoma — a type of skin cancer that can also occur in the mouth and eyes — because it spreads to the brain in 40 per cent of patients in stage 4 of the disease, the highest rate among common cancer types.
Further experiments showed that the melanoma cells that lacked amyloid beta proteins were not able to grow due to an immune attack during the period where they would usually form cell colonies. The original batch of data led researchers to believe that the cancer cells produced the protein in patients’ brains for their own survival. Once the gene responsible for amyloid precursor protein — which becomes amyloid beta — was removed in cancer cells injected into the hearts of mice, the volume of cancer cells detected in the mice’s brains decreased.
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