Over 50% of cancer patients report long COVID symptoms after recovering from COVID-19

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Over 50% of cancer patients report long COVID symptoms after recovering from COVID-19
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Over 50% of cancer patients report long COVID symptoms after recovering from COVID-19 Cancer Coronavirus Disease COVID LongCOVID PASC eLife MDAndersonNews

By Dr. Chinta SidharthanFeb 13 2023Reviewed by Benedette Cuffari, M.Sc. In a recent study published in the journal ELife, researchers investigate the persistent symptoms experienced by cancer patients who previously recovered from acute coronavirus disease 2019 to assess post-acute sequelae of COVID-19 in cancer patients.

One of the generally accepted definitions of PASC is persistent symptoms or the onset of delayed complications at least four weeks after recovering from acute COVID-19 requiring hospitalization. However, several studies have also reported the occurrence of PASC in outpatients who experienced mild severe acute respiratory syndrome coronavirus 2 infections. Furthermore, the prevalence of PASC among the general population varies widely between 10% and 87%.

A longitudinal cohort assessment was conducted based on the remote monitoring of patient-reported outcomes and regular clinical care visits. Follow-ups continued until May 2021. Persistent symptoms or the onset of new symptoms related to COVID-19 beyond one month from the initial COVID-19 diagnosis and extending up to 14 months were used to define long COVID or PASC. Symptoms included headaches, fever, fatigue, dysgeusia, anosmia, myalgia, cough, dyspnea, tightness in the chest, nausea, diarrhea, difficulty sleeping, and difficulty in performing daily activities.

Factors such as the type of cancer, age of the patient, lymphocytopenia, neutropenia, hypoxia, hospitalization during COVID-19, multiorgan failure, type of intervention, and severe disease were not associated with an increased risk of long COVID. Nevertheless, follow-up results showed that the no-PASC group exhibited a significant association with hypertension.

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