Researchers who tracked the replacement of Delta by Omicron in the UK in December 2021 report large falls in infection prevalence among adults who received a booster shot and vaccinated older children compared with unvaccinated younger children.
The geographical distribution was based on the postcode of the participant’s home address of the positive swabs with determined lineages and at least 50% genome coverage. Delta infections are presented in green, and Omicron infections in orange.
Based on the 56 Omicron variants detected out of 378 positives sequenced for swabs obtained from 1 to 17 December 2021, we estimate a prevalence of swab positivity for Omicron in England of 3,700 between 1 and 6 December, 142,200 between 7 and 12 December, and 664,800 between 13 and 14 December – assuming 100% sensitivity and with a weighted prevalence of 1.32%, 1.58%, and 2.14%, respectively.
The highest weighted prevalence in round 16 by age was observed among 5 to 11 year-olds who in December 2021 were not eligible for vaccination. Prevalence was 4.74% which was similar to that observed in round 15 at 4.76% . Out of the 97,089 individuals included in round 16, 84,185 gave consent for linkage to their vaccination data. Based on the linked data, in round 16 76.6% of participants aged 12 to 17 years had received one or two vaccine doses more than 14 days prior to swabbing .
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