A small number of HIV-infected cells remain in the tissues of people living with the virus and who are undergoing antiretroviral therapy. These viral reservoirs, real obstacles to the cure of HIV, have long been known to exist.
is interrupted, are concentrated in the deep tissues of the spleen and lymph nodes, organs of the immune system.
"We owe these results first and foremost to the generosity of two Canadian men who were at the end of their lives, suffering from HIV and on antiretroviral therapy," said Chomont. "By donating their bodies to science, these men made a unique contribution to our work. It is extremely rare to have access to post-mortem analysis for the presence or absence of viral reservoirs in so many organs of the sameNicolas Chomont, professor at Université de Montréal and researcher at the CHUM Research Centre and Caroline Dufour, doctoral student at UdeM.
Using a protocol for analyzing the few viral genomes persisting in tissues, she was able to identify the organs in which"live" HIV preferentially hides.and spleen," said Chomont."In the tissues of the Edmonton participant, they were found predominantly in the same organs, although lower concentrations could also be detected in other tissues.
Ireland Latest News, Ireland Headlines
Similar News:You can also read news stories similar to this one that we have collected from other news sources.
Medicinal cannabis and its impact on patient-reported outcomes in chronic healthResearchers evaluated health-related quality of life and other outcomes in patients taking medicinal cannabis.
Read more »
Mental health worsens as credit crunch bites, with youngest hardest hitAlmost half of 25 to 34-year-olds said their mental health had deteriorated, researchers found, as rents rise at highest rate since 2016
Read more »
Musashi-2 protein plays key role in the regulation of mass and metabolic processes in skeletal muscleResearchers from Tokyo Metropolitan University have shown that the protein Musashi-2 (Msi2) plays a key role in the regulation of mass and metabolic processes in skeletal muscle.
Read more »
Unlocking the secrets of our body's first line of defense against strep throat and moreResearchers have mapped the complex structures of secretory immunoglobulin A (sIgA) in interaction with human CD89 and Streptococcus pyogenes M4, offering new insights into how our first line of mucosal defense operates. The study reveals the intricate ways these components may influence each other, impacting both bacterial survival strategies and host immune responses.
Read more »