A new study brings scientists closer to an elusive goal: figuring out how to outsmart humans’ biological clocks to slow the aging process and keep people healthier, longer
is significant because it demonstrates that calorie restriction may also slow aging in humans.
A group of researchers, led by scientists from the Columbia University Mailman School of Public Health, used data from a trial called Comprehensive Assessment of Long-Term Effects of Reducing Intake of Energy , which tracked a group of more than 200 healthy adults ages 21 to 50 who did not have obesity. Some of the participants were directed to reduce their calorie intakes by 25% for two years, while the rest of the group stuck to their normal diets.
For the new study, the researchers wanted to see if people who restricted calories also aged more slowly than those who ate normally. To find out, they used blood samples taken when the study started, at the one-year mark, and at the two-year mark to look for signs of aging in participants’ DNA.biological ages
, regardless of how old they were chronologically, based on the state of their DNA. Using those methods, the researchers didn’t observe any significant changes after two years of calorie restriction. The third model was meant to find the rate at which someone is aging, rather than their current biological age. Under that framework, the researchers found that two years of calorie restriction led to a 2% to 3% slower pace of aging. That may not sound like much, but, according to the study’s authors,
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