Rising alcohol consumption in China linked to increased risk of 61 diseases AlcoholConsumption DiseaseRisk PreventiveMeasures HealthImpacts Alcohol Chins PublicHealth HealthAwareness AlcoholRelatedDisease NatureMedicine
By Tarun Sai LomteJun 12 2023Reviewed by Benedette Cuffari, M.Sc. A recent study published in Nature Medicine evaluates the associations between alcohol consumption and the risk of diseases in Chinese adults.
Epidemiologic studies involving Western populations have reported the hazards of consuming alcohol for numerous diseases, including cancers, cirrhosis, cardiovascular disease , and infectious diseases. However, studies conducted in Western populations may not apply to the Chinese population due to marked heterogeneity in disease patterns and alcohol consumption.
Morbidity data were obtained from disease registries and the health insurance system. All recorded injuries and diseases were reviewed. The major diseases likely to be causally linked with alcohol consumption, according to the World Health Organization , were also analyzed for associations with consumption.
Related StoriesEx- and non-drinkers were more often older with poor self-rated health as compared to current or occasional drinkers. Heavy drinkers were primarily rural residents with lower education, unhealthier lifestyle, and higher average blood pressure than moderate drinkers, the latter of whom consumed less than 140 g/week.
Alcohol consumption in males was significantly associated with elevated risks for 61 disease outcomes. Only 28 of these 61 diseases were considered by the WHO as alcohol-related, of which included six cancers, tuberculosis, diabetes, hypertensive disorders, cerebrovascular diseases, pneumonia, pancreatitis, cirrhosis, alcoholic liver disease, myopathy, chronic ischemic heart disease , and external causes of harm.
ALDH2-rs671 and ADH1B-rs1229984 showed a strong association in males with alcohol consumption. The genetic instrument predicted a 60-fold difference in the average alcohol consumption across genetic categories in males. The predicted average alcohol consumption was positively associated with established and new alcohol-associated diseases among males.
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