The Asia-Pacific Colorectal Screening scoring system, combined with a stool DNA test, could improve the detection of advanced colorectal neoplasms and limit colonoscopy use, according to a new study. GITwitter MedTwitter
The Asia-Pacific Colorectal Screening scoring system, combined with a stool DNA test, could improve the detection of advanced colorectal neoplasms and limitAlthough a colonoscopy can detect bothand precancerous lesions, using it as the primary screening tool can cause barriers due to high costs, limited resources, and low compliance, wrote Junfeng Xu of the gastroenterology department at the First Medical Center of Chinese PLA General Hospital, Beijing, and colleagues.
Developed by the Asia-Pacific Working Group on CRC, the APCS score is based on age, sex, smoking status, and family history of colorectal cancer. Those with a score of 0-1 are considered low-risk, while scores of 2-3 are considered moderate-risk, and scores of 4-7 are considered high-risk. Based on the APCS score, 946 participants were categorized as high risk, and they had a 1.8-fold increase in risk for advanced neoplasms , as compared with the low- and moderate-risk groups.
"The primary strength of the study was that all patients eventually received colonoscopy, allowing for the best estimate of strategy sensitivity for advanced colorectal neoplasia," he said.
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