Risk factors associated with type 2 diabetes-related mortality Cancer riskfactors CVD Type2diabetes diabetes KidneyDisease Cardiovascular PLOSMedicine HKUniversity
By Bhavana KunkalikarFeb 5 2023Reviewed by Benedette Cuffari, M.Sc. In a recent study published in PLoS One, researchers assess population-attributable risk variables for cause-specific and all-cause mortality due to type 2 diabetes.
As both the incidence of risk factors and the robustness of their relationships with mortality change by age, there may be significant age-related variation with respect to the contribution of risk variables to the mortality burden in a population. In patients with type 2 diabetes, the leading risk factors associated with cause-specific and all-cause mortality across different age cohorts remain unknown.
People with type 2 diabetes who were eligible for the present study were participants of the RAMP-DM between January 1, 2000, and December 31, 2019, and were at least 18 years old at the time of evaluation. The study was scheduled for September 2021, and the analysis was conducted from September 2021 to March 2022.
In terms of LDL-C, HbA1c, and systolic blood pressure /diastolic blood pressure , 54%, 50.2%, and 33.5% of individuals did not meet the recommended treatment targets, respectively. The current smoking prevalence among the participants was 13.4%. The absolute mortality risk rose with increasing age at baseline. The crude all-cause death rate was ten times greater among individuals aged 75 years or older than among those between 18 and 54 years of age.
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